Losartan

Alternative Medicine
The following information is specific for alternative and complementary medicine. For additional evidence-based information on diseases, conditions, symptoms, diagnosis, treatment and wellness issues, continue searching the Healthwise Knowledgebase.

Also indexed as:

Cozaar

Combination List

Combination drug:

Losartan is used alone or in combination with hydrochlorothiazide (Hyzaar®) in the treatment of high blood pressure. It is a type of drug called an angiotensin II receptor antagonist.

Herbs

Summary of Interactions for Losartan

Depletion or interference None known
Adverse interaction None known
Side effect reduction/prevention None known
Supportive interaction None known
Reduced drug absorption/bioavailability None known
Other (see text) Potassium

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Supplements

Potassium

Losartan has caused significant increases in blood potassium levels.1 Potassium supplements, potassium-containing salt substitutes (No Salt, Morton Salt Substitute, and others), and even high-potassium foods (primarily fruit) should be avoided by those taking losartan, unless directed otherwise by their doctor.

Other Interactions

Food

The intestinal absorption of losartan may be reduced up to 10% if taken with food.2 Although this is a minor reduction, losartan should be taken an hour before or two hours after food for maximum effectiveness.

References

  1. Perazella MA. Drug-induced hyperkalemia: Old culprits and new offenders. Am J Med 2000;109:307-14 [review].
  2. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc., 2000, 1769-72.

Last Review: 01-21-2009

LogoCpyrt.gif

Copyright © 2010 Healthnotes, Inc.  All rights reserved.  www.healthnotes.com

Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article.

Learn more about Healthnotes, the company.

Learn more about the authors of Using Medicines with Vitamins and Herbs

The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires August 2010.


 Go to top of page Go to top of page 


This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Click here to learn about Healthwise
Click here to learn about Healthwise
Topic Contents
 Combination List
 Herbs
 Interactions with Supplements
 Other Interactions
 References